Consider using conditional formatting styles wisely. Instead of applying complex rules that involve multiple conditions and formatting actions, try to simplify the rules. Simple conditional formatting rules are generally faster to process on large datasets.

Another approach is to split the large dataset into smaller, manageable ranges and apply conditional formatting to each range separately. By doing this, you distribute the formatting workload across multiple smaller ranges, making it more efficient.

If you often find yourself applying the same conditional formatting rules to multiple datasets, it might be beneficial to create a custom function using Google Apps Script. This allows you to encapsulate the formatting logic and apply it to any range with a single function call.

One efficient way to apply conditional formatting to a large dataset in Google Sheets is by using custom formulas as the condition. Instead of applying conditional formatting to each cell individually, you can select the entire range and set up a formula-based condition that only works on the visible cells. This can greatly reduce the processing time and enhance performance.