One option to improve Excel performance with large datasets is to use Power Query. By importing and transforming the data using Power Query, you can optimize memory usage and reduce the amount of data loaded into Excel. Another approach is to use Excel's Table feature, which helps organize and manage large datasets more efficiently. Additionally, you can disable unnecessary calculations, formulas, and features like automatic cell formatting to reduce processing time.

While Power Query and Excel Tables are great options, another technique to improve performance is to use PivotTables. PivotTables allow you to summarize and analyze large datasets quickly, with the advantage of dynamic updating as you make changes to the underlying data. Another way to boost performance is by enabling the 'Manual Calculation' option, which allows you to control when formulas are recalculated. This can significantly reduce processing time when working with large datasets.

In addition to Power Query, Excel Tables, and PivotTables, you can enhance Excel's performance by using the 64-bit version of Excel if your computer supports it. The 64-bit version allows Excel to utilize more memory, thereby enabling smoother handling of large datasets. Another useful technique is to create calculated columns using Excel's Data Model feature. By offloading some calculations to the data model, you can reduce the load on Excel itself and improve overall performance.